Written by IGCSEPhysics Content Team · Physics subject adviser: K. S. Tan, 15+ years teaching IGCSE Physics · Checked against the Cambridge IGCSE Physics (0625) 2026 to 2028 syllabus
Different types of ionising radiation have different medical applications, chosen because of their penetrating power and ionising ability.
Diagnostic uses
X-rays (imaging):
- X-rays pass through soft tissue but are absorbed by bone and dense tissue.
- A detector (photographic film or digital sensor) behind the patient creates an image.
- Used for detecting fractures, dental problems, chest infections.
Gamma cameras (tracer studies):
- A patient ingests or is injected with a gamma-emitting radioisotope (tracer).
- A gamma camera outside the body detects the emitted gamma rays.
- Used to image organs (thyroid, kidneys, heart) and detect abnormalities.
- The tracer must have a short half-life (hours) so it decays quickly and minimises exposure.
PET scans:
- Use positron-emitting tracers (e.g. fluorine-18).
- Produce detailed 3D images of metabolic activity.
Therapeutic uses
Radiotherapy (cancer treatment):
- High-energy gamma rays or X-rays are aimed at tumours to kill cancer cells.
- The beam is rotated around the patient so healthy tissue receives a lower dose.
- Multiple sessions are needed because not all cancer cells are killed in one treatment.
Targeted radiotherapy:
- Radioactive sources (e.g. iodine-131 for thyroid cancer) are taken internally and concentrate in the target organ.
Why gamma is used for tracers
- Gamma penetrates the body (alpha and beta would be stopped before reaching the detector).
- Gamma is the least ionising (lower risk of cell damage).
- Short half-life tracers (e.g. technetium-99m, hours) decay quickly, reducing long-term exposure.
Common errors and how to correct them
- Saying alpha particles are used as medical tracers. Alpha cannot penetrate the body; gamma is used.
- Confusing tracers (diagnosis) with radiotherapy (treatment).
How to apply this in an exam
Name the specific type of radiation used and explain why (penetrating power, half-life). Describe the safety measures taken to protect the patient and medical staff.
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